Absolutely yes, but not to the point that you should be concerned. In the original design, of any engine, a compromise of performance/longevity has to be made. A remap will lean the compromise more to the performance side of things. Extra strain on the drivetrain puts more stress on the clutch in particular - but that is considered a servicable item anyway and isn't expected to last the life of the car.
To put some real numbers to the matter for you, my last car was standard until 60k miles. It was then remapped and modified in other ways to increase the power to about 70bhp above standard. The clutch -just- started slipping under heavy load in high gears a week or two before I sold it with 130k miles on the clock. I had no other engine issues (not related to the remap anyway) for those 70k miles of driving pleasure.