I can't help thinking Thai is talking about the sort of flat spot that happens on cars that are stood up for ages. The type that you can get rid of with a foot pump...
Certainly stood up tyres don't wear unevenly...
I see marks in the fast lane of the M3 that look like someone has been larking about with the handbrake at silly speeds though - that will give you a flat spot...
TBH I would probably be concerned enough about it to want it off my motor. I have no idea what is causing it but my brain would certainly spend too much time on wondering what the possibilities were that £60 or so for a new one would be economical relief IYKWIM...