You have to select the correct COM port in settings. When you attach the cable to the PC, look in device manager for it, it will say which com port it's assigned. Select this as the Com port in the Vag Com settings. Then plug into the car (no need to start, just turn key to position 2). It should then run that initial setup. Then click 'Save'. So you only do it this once.
Check out the Ross Tech website, or do a search here. The info is there, it's easy enough.
