Yes, it should work. The 1K0951605C Bosch siren is effectively the later replacement for the older 1K8951605 (Cobra) unit used on Mk5/Mk6 platform cars. VW superseded the earlier 1K8 part numbers with the 1K0 versions, and they're listed as interchangeable.
Just make sure the connector is the same (3-pin) If your old siren has failed, it's usually because the internal rechargeable battery has leaked and damaged the circuit board, which is a very common Mk5/Mk6 issue