Slightly off topic again, this whole sub-enclosure thing.
I'm not an ICE expert, but I'm a sound engineer and have studied acoustics.
The bigger the speaker, the more air it can move, so therefore it needs a bigger enclosure.
The bigger the enclosure, the lower the resonant frequency * (ie it will give you that deep d'n'b sound).
The smaller a speaker, the quicker it can move, so your 12inch sub will give a punchier bass, but because the sub and enclosure is smaller, it won't resonate at the lower frequencies, so won't give you as deep bass as the 15inch.
As for using the two subs together, there are no technical problems, so long as a) they get the same mono signal, b) they both face the same direction.
The 15inch sub will give you that lower deep bass, and the 12inch will give you the slightly higher kick/punch bass sound. Any sounds/frequencies in between that both subs can provide will just be louder because it's coming from two subs and soundwaves (ie air pressure) always add up, making it louder, provided that (as above) a) they are from the same source/mono signal and b) the speakers are firing the same direction.
Basically: If you want to use both subs, go ahead, run them both in mono, and pointing the same direction. If you get a point where the two subs act together and you get annoying frequencies, you can tune that down with your EQ to your own taste.
As for your build. Here are three options.
1) just use standard sub enclosures and fix them down
2) build the whole thing with MDF and cover with carpet
3) build the base of it with MDF, then mould something really slick, rounded and shiny with fibreglass over the top
Make sure it's on a big bit of mdf though, so you can lift it out and get access to your spare wheel.
If you don't need a spare wheel, you could mount a sub or amp in the wheel well and make a feature of it.
Remember that all the MDF, subs and amps will add weight, hence why some like the lighter fibreglass option.
You will also need to run decent power cables from your battery cos amps for subs take a lot of power.
*If you don't know what a resonant frequency is, it's the frequency as which the object/box/enclosure naturally vibrates/resonates.
To test this out, grab 2 wine glasses, one bigger than the other, place on a table. now hit the side of the smaller one with a pen, now hit the bigger glass. The bigger glass has a lower resonant frequency, and the smaller glass will give a higher "ding" sound.