Ideally yes, especially if you are mapped already.
Your boost, timing and everything else altered in a remap will be adjusted to get the best from the OEM setup, and if it was weak, then you might be seeing more/higher readings than what you mean to.
An example MAY be: Having fuelling adjusted to say 12psi boost at 4000-6000rpm and you are able to hold 14-15psi boost between the same range, thus you might end up running lean.
Heres a plot of a forge actuator put on and ran back to back without mods from R-tech.....speaks for itself!