Low mileage can be a blessing or a curse, IMO. If it has been a city car, with the inevitable crap roads, speed bumps, stop-start traffic, etc that comes with that, the wear and tear could be greater than a car with many more miles on it. Same applies if it has been a weekend toy that has only covered hard-but-fun miles.
The problem is it's practically impossible to know its real history, especially when buying from a dealer.