I would say that unless you are paying your mortgage off super fast, with 50% equity, you are going to (at the bare minimum) break even, perhaps make a semi decent profit on it. With that in mind, I would go for it, with the following proviso's...
1. Go through a reputable and recommended letting agent - a fully managed package is somewhere between 10-12% of rental income.
2. Ensure you have a buy to let mortgage. You will probably get a slightly worse rate than a standard mortgage but at the moment rates are low, so it could be a good time to change mortgage anyway. Remember that you might get a 'lock-in' period for your new mortgage (normally the same amount of time as your fixed rate if you get it), so ensure you intend to rent for longer than this.
3. Get a decent landlords insurance policy.
4. Get (something along the lines of) British Gas Homecare - the best cover you can afford.
5. Ensure you let the taxman know about it - you'll need to pay tax on any profit.
6. Once it is rented out, ensure you put away the majority of the first 6 months/1 years rent (or profit if you use it to pay your mortgage) just in case you get a period of it not renting out - some letting agents will guarantee the property is rented out for something along the lines of the first 6 months, so you'll be safe for a while, but after that, there's no guarantees.
Remember as well, that any expenses you have with the house (letting fees, insurance, homecare) can be offset against tax (IE, you get tax relief on them and will therefore only pay tax on the profit, rather than your rental income).
I rent my house out as I am out of the country for 4 years - although I don't make a profit, it's nice to have someone paying my mortgage for me!